Molecular Biology
Your body is made up of trillions of cells. Each cell is a copy of a single cell that divided itself to make all of the cells in your body. Your cells need instructions to create who you are. Your DNA, genes and chromosomes work together to tell your body how to form these cells and how they should function.
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Every cell has a nucleus which contains the 23 pairs of chromosomes (46 total) wrapped in a double helix formation. Your DNA is carried in the chromosomes. DNA is responsible for building and maintaining your human structure. Genes are segments of your DNA, which give you physical characteristics that make you unique.
Another vital cell component is the ribonucleic acids or RNA. RNA is involved in many functions within the living cell including gene expression, protein synthesis, catalysis, regulation, and viral infection.
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​​​​​​​​​​​​Molecular biology is a field of science concerned with studying the chemical structures and processes of biological phenomena of nucleic acids (e.g. DNA and RNA) and protein molecules, and how these molecules interact and behave within cells. ​
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One of the greatest scientific feats in history was the publication of the first sequence of the human genome (i.e. DNA) in 2003 by the Human Genome Project. By providing the fundamental information of the human blueprint, this publication has accelerated the study of human and molecular biology. These studies are now yielding a growing base of knowledge on molecular biomarkers (i.e. proteins, genes and other markers) and the connection that they have to diseases.

Protein
Synthesis
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Cell Generation
Base: A letter
adenine (A), thymine (T), guanine (G) cytosine (C)
DNA
deoxyribonucleic Acid
There are three main types of RNA found in all living organisms:
The sequence of Bases determines the instructions encoded in the Genes and the order which amino acids sequence (i.e. the order that the recipe's ingredients are mixed), the components which include:
Nucleotides - The building blocks of nucleic acids, including DNA and RNA
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Coding regions or exoms - Contain the instructions for making proteins.
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Non-coding regions including regulatory sequences, pseudogenes, repetitive DNA and introns - The purpose is to regulate gene expression and control various cellular processes, when and where genes are turned on or off, and to provide sites for specialized proteins to attach and either activate or repress the process by which the information from genes is turned into proteins (transcription).
TRANSCRIPTION
RNA
Ribonucleic Acid

46 Chromosomes:
23 chapters in each book
Variant : A spelling change

Genome
Father's
recipe
books
Genome = complete set of DNA
GAATAAATTA
CTGGTCTTATT
TCCAGGCCTT
AGTAACGTAA
AGTAATCAGT
CAAACTTCGG
Molecular Biology Processes
A Child's Genome is based on each parent contributing 50% each of the child's DNA
A Variant is a change in the 'spelling" of a recipe (Gene). A variant can be inherited from a parent, called germline variants, or acquired during our lifetime, called somatic variants. Most have little to no impact while some can affect our health and development (pathogenetic).
More than 20,000 recipes (Genes) are organized in Chapters in the Recipe Book, called Chromosomes, with 23 pairs forming the DNA double helix.
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22 of these pairs are called autosomes. The other pair are called allosomes contaning the sex chromosomes: X and Y.

Mother's
recipe
books
Genome
46 Chromosomes:
23 chapters in each book

GAATAAATGC
CTGGTCTTATT
TCCAGGCCTT
AGTAACGTAA
AGTAATCAGT
CAAACTTCGG
GenomeChild's
Recipe
Books
Gene = recipe in the book

Protein translation plays a crucial role in cell development by synthesizing proteins that are essential for various cellular functions.
